EP 95 - A Longer, Better Life by Fasting - Mimicking with Dr. Joseph Antoun

EP 95 - A Longer, Better Life by Fasting - Mimicking with Dr. Joseph Antoun

Studies show that a periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance. That's your brain and health span, which means a longer life. How do you do this? In today's episode, I'm interviewing Dr. Joseph Antoun. He wanted to be at the forefront of changing our current healthcare system of sick care to a more proactive approach, which means taking care of our existing good health. The good news is with PROLON fast, you get to actually EAT. Let's dive in!

‘’When the car gets worn down, you go to the pit stop - the mechanic comes, they change the wheels. They put more oil and gas and they fix everything going wrong. This is what happens during a prolonged fasting of two to three days.’’
-Dr. Joseph Antoun
’Our body's not getting any rest from food, from stress, from lack of. Food is the only product we put in our body every day of our life. So let's start there. Let's give our body a break.’’
-Dr. Joseph Antoun

TIMESTAMPS

2:35 A little bit about Joseph’s background

4:55 Getting ahead of the issue by affecting lifestyle changes versus just the symptoms

6:47 How much time does Joseph spend studying nutrition in his education

8:08 The impact of nutrition and what we eat in terms of our overall health

11:29 PROLON – how it was made, the mission and goals

16:01 How our body fixes itself to survive

19:44 The concept of eating while your body is recognize it as fasting

20:01 How long and how often should people do this?

23:43 Is this safe for people with diabetic/sugar-related conditions?

28:08 Can you preserve your muscle mass without compromising that and also shed body fat?

29:51 Feedback from professional athletes

34:05 Anecdotal examples on what Dr. Joseph has personally seen

35:12 The four huge benefits to fasting

40:32 Handling even the mental health issues with proper nutrition and fasting

43:00 Bio versus chronological biological age

48:26 The best ways to reach out to Dr. Joseph

49:11 If Dr. Joseph could have any meal cooked by anyone, what it would be
 

RESOURCES


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FULL TRANSCRIPT

[00:00:00] Mareya: Studies show that a periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance. That's your brain and health span, which means a longer life. Now that sounds pretty good to me, but how do you do this? In today's episode? I'm interviewing Dr. Joseph untune. He always knew that he wanted to help others through medicine.

[00:00:24] But eventually he figured out that medicine was actually sick care. Treating patients after their health had already declined amen to that. So he wanted to be at the forefront of changing our current healthcare system of sick care to a more proactive approach, which means taking care of our existing good health.

[00:00:45] And that is exactly what he is doing. As the CEO of El Nutra and the very popular ProLon diet, which we're gonna talk about in this episode. But Hey, our friends over at ProLon have given [00:01:00] us a code for 15% off. All you have to do is use the code, eats cleaner at checkout and that's pro lawn fast.com pro lawn fast.com.

[00:01:13] The good news is with this fast, you get to actually. Eat. Yes. I said it. These types of diets help you get all the benefits, but don't leave you hungry. Let's dive in for some more food for thought.

[00:01:35] Hi, I'm Maria, otherwise known as the fit foodie. I'm a chef holistic nutritionist, author, inventor, and mom. And I wanna welcome you to my podcast. It's called recipes for your best life. And with every episode, I'm peeling back the onion on fitness, nutrition, health, wellness, and family. The truth is you are the chef of your life.

[00:01:59] And for every. [00:02:00] Hiller. There's a great recipe worth sharing. So every week we'll explore them together. Think of it as food for thought that you can really sink your teeth into. So join me and let's squeeze the joy out of this life. Cuz you only get one. Can I get a fork? Yeah. Dr. Anton, welcome to the show.

[00:02:20] Thank you, Maria. It's so nice to have you. And I, I think we speak a very similar language, so I'm always very excited to speak to people with a medical background, um, that speak nutrition. But, um, let's talk a little bit about your expertise. Can you just share a little bit about your background? 

[00:02:40] Dr. Joseph Antoun: Yeah, for sure.

[00:02:41] Um, and thanks for hosting me today. I, um, I started my life as a medical doctor and my passion was to, you know, help patients. Um, actually I wanted to cure them from their diseases. Um, and then when the more I get into medicine and the more I started doing my rotations, I, [00:03:00] it was a part that was fulfilling, of course.

[00:03:02] And there was another part that was missing because I felt I mainly am putting people on pills for every day of their life. I wanted to be a cardiologist. I was doing my rotation at mass general at Harvard. So I was like pretty excited as a medical student to be in the top center. But at the same time, there's a part of me.

[00:03:21] That's saying, wait a second. And just seeing people after they have a heart attack, I'm seeing I'm not practicing healthcare. I'm prac practicing sick care. And then, and then I give them a, a pill for cholesterol that they have to take for the rest of their life. It doesn't reverse healthy cholesterol.

[00:03:40] I'm giving them a pill for their blood pressure that they have to take for the rest of their life. I'm giving them a pill for diabetes, blood, sugar that they have to take to the rest of. Actually, it's not that they just have to take them. They're gonna add more pills to those. Mm. That part of medicine did not fulfill me.

[00:03:57] I was like, wait a second. Where, why don't we [00:04:00] reverse these conditions? And, and God bless the biotech industry and, and, and medicine, because you do need that help. But the disappointment. All medicine were this, it wasn't like there's a lifestyle medicine that can help us reverse these conditions. And then whenever you fail of that, 20% of medicine would be a pill based medicine.

[00:04:22] So it was a hundred percent, was a pill based medicine. And 90% of the a hundred percent was a pill that will never reverse the health condition. And that was my frustration. So I decided to, after graduation, I left and I studied health quality in public. My goal was, can I, you know, advocate for a better healthcare system that is more preventative, that's more true healthcare and it can put more money into solutions, not mitigations in a secure system.

[00:04:53] Mareya: Right. So you're, you're really trying to get ahead of the issue by affecting [00:05:00] lifestyle changes versus just the symptoms, right? Yeah, 

[00:05:05] Dr. Joseph Antoun: because. What, what they don't teach us in medicine is, is 80% of the reason why you get cancer or diabetes or cardiovascular. Maybe not Alzheimer's is turning out to be, I mean, aging, for sure.

[00:05:20] You don't get Alzheimers age 20 or diabetes at age 22 or most cancers are age 24. So aging is the biggest driver and lifestyle, which accelerates your aging or decelerates your aging. So let me simplify this. The guy that was sitting across from me when I was a physician who has high blood pressure, high blood sugar high, he was in 22.

[00:05:44] Yeah. He was 58. And guess what? He's stressed as a father paying college for his kids and he's, he's working so hard. He's gaining weight, which was easy for him to get rid of 20 years ago. And now he's not getting that belly fat. Right. And [00:06:00] he's more sedentary now that he comes back tired and home. And so the profile was clear.

[00:06:04] I was like, why are you giving him five pills? Just help him lose the weight, help him be a little bit happier and less stressed, help him with his sleep and help him get rid of his fat, probably the blood sugar of blood pressure and the blood vessel will drop. Yes. And that was not our solution. Our solution was a pill for every one of those.

[00:06:21] And by the way, while he's leaving the clinic, Hey, you should eat a little bit better, a little bit healthier. And he say, yeah, yeah, I know. I'll try next. That was, it should have been the flip story. It should have been 60 minutes of lifestyle coaching. And then 10 minutes saying, if you're gonna fail on all this, I'm gonna have to give you medicine.

[00:06:40] Mm. 

[00:06:41] Mareya: So do you, can I just ask you an honest question as a physician? How much time do you spend studying nutrition in your education? 

[00:06:54] Dr. Joseph Antoun: So I had one hour in my education. And, um, and actually Harvard did the [00:07:00] survey and 70, 30% of the doctors said they, they don't feel they're trained enough in nutrition. And this is just nutrition.

[00:07:07] I mean, ask me about stress zero hours on stress, zero hours on, on sleep, zero hours on social capital, the, this, the shocking outcome. When you study Senti areas, people that, that live a hundred and beyond, right? This should be medicine. Medicine should be about aging. And this is where they're like, what do you mean aging?

[00:07:29] Yeah. Yeah. We're gonna die. 90% of us will die out of cardiovascular disease and or diabetes and or cancer and or Alzheimer's or journey. And guess what the biggest trigger of all these four, they tell us in medicine is genetics and or something went wrong. Now it's just aging can not explain a role of course, but even if you have the APO gene.

[00:07:53] You're not gonna get Alzheimer at age 20, you're gonna still get it at age 75 and, and 70 and 80. 

[00:07:58] Mareya: So I I'm just so [00:08:00] fascinated, fascinated by this because you know, we know so much about the impact of nutrition and what we eat in terms of our overall health. And I'm just flabbergasted by why that is not. A priority in education, but I'm thankful for people like you who are setting the record straight.

[00:08:22] So, 

[00:08:23] Dr. Joseph Antoun: but I'll tell you why. Actually I did look into this. I'm also surprised as you were into why we didn't get this education. And, and guess what, because a lot of it is to, to blame the nutrition companies as well. Right? And this is why I spent today in a nutrition company. If you look at the, the word has more nutrition has probably a hundred times more nutrition company than pharma companies.

[00:08:47] And, but you are a nutrition expert. Tell me four articles that you've seen four randomized evidence based medical. [00:09:00] Articles that nutrition companies have done to show that their food will help you reverse diabetes or cancer or Alzheimer's or any of these claims that they try to. Name 

[00:09:11] Mareya: one. I mean, and I think that's, that's, you know, it, it means you're gonna do a deep dive and you're gonna put the attention and money towards it.

[00:09:19] And that's just not really a priority. Right? Exactly. 

[00:09:22] Dr. Joseph Antoun: So the that's, the problem is nutrition. The, the, the problem is not the doctors, because the doctors are hungry to help their patients. The problem is the nutritional business, because they're less regulated. They don't wanna go through the hoops of science.

[00:09:35] They don't want to. And, and have the science uncover the artificial things that they use. They, they don't wanna help the science uncover the high saturated fat that they have to make it taste better. They don't want science. So they go to development product, they write a book, they talk to a couple of influencers and they wanna, they wanna sell you the product and, and, and you have multibillion dollar nutrition companies that can easily do multiple twin [00:10:00] trials and you see nothing coming out of them.

[00:10:02] So, so the blame is literally. On both sides of the aisle. And, and, and they're more, they're both, they're both happy because nutrition is exploiting your pallet to give you something that tastes good so that you keep buying from them, but it's not healthy. And the other side of the aisle before the, before the system reform led by Obama, we, the other side of the eye was getting paid when you're sick.

[00:10:26] So the doctor gets paid when you're sick, then traditionist gets paid when you're sick and the hospital gets paid. When you. And this is what bankrupt the system. We are spending $4 trillion on the healthcare system. And now due to that pseudo bankruptcy policy change, and now the doctors and the hospitals are being paid as an accountable care organization system.

[00:10:46] Now it's a one fee for taking care of you. So if you wanna create profits, so you gotta keep you healthy. And suddenly now lifestyle medicine is a thing. And suddenly now payers and insurance are paying for Nutri. [00:11:00] We as a company, El Nutra were actually among the first companies that Medicaid, Medicare decided to pay for our food were actually reimbursed as medicine now.

[00:11:09] And I'm happy to tell you more about, oh, that's great. Yeah, so well that 

[00:11:13] Mareya: that's a big, that's a big step in the right direction for sure. And I think that, you know, when the simplest thing that we can do, right, every single day, something that we do multiple times a day is look at the fuel that we're putting into our bodies.

[00:11:29] So can you, can you share a little bit about. Your company and what you're doing, because I, I have to tell you, and I shared this with you prior, you know, before, you know, we even sat down to talk. I didn't even look up ProLon, but I had been speaking to somebody about it and she asked me if I was familiar with it.

[00:11:48] And then all of a sudden I started seeing information about it. It was like you were reading my mind or something. So can you share a little bit about your program? 

[00:11:59] Dr. Joseph Antoun: Yeah. [00:12:00] ProLon is, is the first product, uh, in history to mimic fasting and, and it's, it's growing pretty fast. So I'm happy you're hearing about it.

[00:12:08] I'm happy. We're gonna talk about it. Um, but I'll take a first step back to talk about the company and the mission we're called L Nutra L is for longevity through nutrition, right in, in the goal is we all want to live a healthy and long life. This is why we're a longevity company. And we're the only company in the world, by the way, we're the fully issued pattern on promoting longevity and it's on our food, on our nutrition and specifically ProLaw.

[00:12:34] Um, and our goal was to be that company that I told you, the word is missing, which is a company that puts randomized human trials, meaning evidence based proof and testing behind food. So 25 years ago, we started doing like pharma, or basically they call us the Pfizer of food. We do, we do clinical testing on our nutrition, and then we go out, we publish that in top peer [00:13:00] review journals, and we tell you what our food does your life.

[00:13:03] And, and early on, we, we fumble on fasting everyone in the last six years. Talk about fasting. This is a lot of. It's coming from our clients, but we started testing fasting 20 years ago. And, and our biggest discovery was that if you fast for a few hours and a lot of people today skip breakfast, they do the 16, eight, and you know, you lose weight, right?

[00:13:26] You lose weight, you improve your blood pressure, blood sugar, uh, everything that's metabolic. We call it the downstream metabolic health. What we have discovered is that if you go beyond. Few hours a day or two or three, what happens? We were very interested in biologically testing. What are the defense line of the body?

[00:13:46] If you go on a longer, fast, and it turns out that the first line of defense, which is burning fat, the liver can ship in some, we call Neo glucogenesis. You have glycogen in the muscle. So these are the [00:14:00] first line of coloring defense against fasting. After two days. They, they started getting depleted. The buddy goes into saying, Hey, I'm gonna, I'm gonna go bankrupt.

[00:14:10] I gotta bring a new line of defense, natural, right? Hundreds of thousands of years of living on planet earth. We never had food all the time. So naturally the buddy was eating and not eating. Now we eat all the time is why we see all these diseases. But naturally the body actually had Fe and famine cycles and the body knew what to do when our asses were migrating from snow to kind of, you know, shores or coast or, or when there was no food.

[00:14:36] And this, the second line of defense is the cellular line of defense. And this is what excites us the most. So basically the body tells the cells, Hey, I cannot no issue any longer. We're in a big crisis. I helped you the first two days. Or three days now you have to go and look for things that are going wrong inside of you.

[00:14:56] Things that you can consume as new source of calories, right? [00:15:00] Organelles debris, you gotta detox. You get clean, you gotta optimize, you gotta wear a survival mode. You gotta fix yourself. And that process is called autophagic. Or self eat and out of ag happens around day two or three of fasting. You'll read a lot of books and a lot of experts saying it happens in 16 hours is why everyone is doing it and that's, that's dead wrong.

[00:15:22] Um, you know, you skip breakfast. You're not in a crisis. Um, that happens naturally to a lot of people. Um, most studies show that you need two to three days sometimes longer. If you're skinny, you have a high metabolic rate. You're exercising, maybe one to two days. If you have a lot of reserves, you have a little bit more weight.

[00:15:39] You have a low, slow metabolic rate. So you have more reserve on your burn less. Then it will happen around day two, three, or maybe at four fourth day. But let's say most people will get it between day two and three in, in auto one, the noble prize in medicine in 2016, it's a big, big discovery. It's a lot of doctors call it the miracle [00:16:00] of biology.

[00:16:00] This is how our body fixes itself to survive. Right. Imagine a, a car race, a formula, one car race. When the car gets worn down, you go to the pit stop and the pit stop. The mechanic come, they change the wheels. They put more, uh, oil and gas and they, they fix everything going wrong. This is what happens during a prolonged fasting of two to three days.

[00:16:24] um, and, and, and it's the body cleaning the cells. 

[00:16:27] Mareya: So biologic, so it's, it's that cellular renewal, so to speak, right. Kind of the body cleaning out. I almost envision it like a little broom, you know, sweeping out the old stuff to make way for the good stuff, the new stuff, right? 

[00:16:40] Dr. Joseph Antoun: Yeah. It's part of survival of being new and effective.

[00:16:44] and, um, and, and now the issue is that who's gonna do three and four and five days of water fast, so difficult. But when we did the trials in mice first, they were like, you know, for example, cancer cure rate went from [00:17:00] 36% to 93%. Wow. Diabetes reversal rate was off the roof. We're talking about hundreds of percent higher.

[00:17:07] So we showed this data to the national issue of. And they were fascinating with it. And we, we, we were not able in humans to do trials on water fast because people couldn't fast for four or five days. And then they said, okay, we're gonna support your labs, your research with money from the NIH, um, to develop the fasting, mimicking diet.

[00:17:29] And basically the fasting mimickin diet is a nutrition that we formulate. Um, you know, the commercial name of prolong. There are others for, for health conditions. Basically, it's the food that we deliver to you at home, uh, bars, soups, snacks, olive, those drinks. So you get your breakfast, lunch, and dinner, but they're specifically formulated to nourish your body, but not to take the cells off fasting.

[00:17:55] And, and I, I need to basically explain that because we will be like where the fucking [00:18:00] fasting is no food, how you're mimicking fasting with food. So to explain that there are two ways the body recognizes food. One way we call. The undercurrent level, meaning the systemic level. When you eat carbs, you know, insulin increases as a response.

[00:18:15] Insulin is a growth factor is a signal that there's food. And if you eat proteins, then insulin like growth factor IGF, one increases telling the body, Hey, there's protein. So the body at the, at this systemic level recognizes foods through insulin and IGF. They're both growth factor. There's a signal of growth.

[00:18:33] It means there's. And so the, our food is specifically designed to not spike, insulin and insulin, like growth factor. They barely increase and they plateau and then they decrease. So the system at the, at the, at the, at the level of the blood level is not feeling that there's a growth signal. So like, shit, we're still in a fasting signal.

[00:18:55] Mm-hmm and then the food gets into the cell it's specifically [00:19:00] designed to not trigger. The nutrient sensing pathway of the cell. So the cell senses food through three radars, PKA tour and RA, and the, our food is designed to when, by the time it gets to the cell, it is barely triggering these sensors. So basically the body is not feeling the food and the cells are not being the food, although we're nourishing you.

[00:19:24] And, um, and so this is, this is the secret behind the fasting mimicing diet. The body doesn't recognize it and the cells don't recognize it. And therefore we give you the benefits of fasting without having to do the starvation fasting on water. 

[00:19:44] Mareya: Okay. So this is kind of, it, it's a pretty interesting concept because you're still getting to eat, but the body is still recognizing it as fasting.

[00:19:56] Exactly. Is that correct? Exactly. So, so if that's the [00:20:00] case, how. How long. And how often do you recommend that people do this? I mean, is this something that we are supposed to be doing daily or are we supposed to be doing it maybe once a month? Or how, how frequent are we, you know, what is your recommendation on the frequency that we should be, you know, intermittent fasting.

[00:20:22] Yeah. 

[00:20:23] Dr. Joseph Antoun: So this is not intermittent, right? Intermittent fasting is only the 16 hours and you can do intermittent fast. Daily just to lose weight. But if you wanna do the prolonged fasting with prolong, P R O L O N is the five day nutrition that we talked about that keeps your body into prolonged five day fast, and you would lose a lot of weight on average five to eight pounds in just five days, but you would rejuvenate yourself.

[00:20:49] And this is the interesting piece that, that we think is very much a pro longevity. Uh, based lifestyle. So you do ProLon five days, [00:21:00] only two to three times a year if you're healthy. So, and, and by the way, this is how you figured out when a CEO tells you should do my product only three times a year. That should send you a signal.

[00:21:10] Yeah, right. And so if you're healthy, let me give you two profiles. You're 40, uh, you're active. You just have, you know, just few pounds to. Otherwise, you don't have a health condition. You're not that concerned yet. And you wanna do the prolonged fast just to, to rejuvenate yourselves and to move little bit, just a little bit of weight.

[00:21:33] So you can do that once a quarter or three or four times a year only that. So when you go to prolong to buy it just three times, that's it. Now, if you are 55, 60 ish, you feel that, you know, I have a I'm I'm it's, it's difficult to share off your. You're concerned about potentially having a health incident.

[00:21:54] You're kind of feeling the aging on your buddy and you want a deeper renewal. This is when you can do it [00:22:00] four or five or six times per, per year. And, uh, and so these are the two kind of general protocols, three times three to four times or four to six times. If you want a more advanced fasting experience.

[00:22:13] Mareya: So with, is it just, is the, like when you place an order, are you just getting food or are you also getting supplements? 

[00:22:23] Dr. Joseph Antoun: No, it comes with food drinks and supplements for five days. Okay. It gives you everything you need macro and micronutrients for your five days. A lot of people love the fact they don't have to cook.

[00:22:34] They don't have to buy food. They don't have to, you know, go anywhere. Um, it's just five days that you stick to. There's a schedule of what to eat when throughout the day, and you have to stick to it. So your body really recognizes no food and keeps you in a fasting mode. 

[00:22:50] Mareya: Right? And is it all plant based?

[00:22:54] Dr. Joseph Antoun: It's all plant based. It's natural, gluten free, so very high premium [00:23:00] ingredients. And that's actually thank you for asking this question because besides the fasting fact, this is a very healthy. Plant based five days to take your body to a lot of people, uh, detox with it. A lot of people do it to change their microbiome to a plant-based microbiome.

[00:23:17] Um, it's very rich in, in high premium, uh, nuts. So you have academia nuts and almond and pecan, and these are the most premium thing, expensive thing you can buy from nature. Um, they're rich in very healthy fats. They have the right plant-based amounts of protein and they have complex car. That would not spike your insulin.

[00:23:39] So definitely very healthy from an agreement based perspective. 

[00:23:43] Mareya: Mm-hmm okay. Wonderful. Um, so let me ask you a question, because this is something that has come up quite often in the groups that I coach. If somebody is diabetic, somebody has, um, a blood [00:24:00] sugar related, you know, medical condition. Is this going to be a problem for them?

[00:24:07] Dr. Joseph Antoun: Well, uh, interesting. We, we just, we published last week, an article on diabetes, um, on diabetes kidney with six cycles of ProLon and we're about to publish an article on 12 cycles of ProLon. So I didn't wanna talk diabetes. We don't claim on the product since we mentioned the name problem, but, um, we, we are launching in Q4 of this year.

[00:24:31] The diabetes remission program, because we're showing that if you do around six prolongs per year with under the supervision of nutrition, so I'm very happy. You're saying you're supervising your group, um, that we're showing a seven to 800% chance of remission versus just doing Metformin or, or the traditional drugs.

[00:24:53] Wow. So, so what you wanna do is if your patient is on, you know, Metformin or, or, [00:25:00] or oral, we're not seeing, um, we definitely, definitely should consult with the doctors, but, um, what we're gonna recommend is that they can do the prolong on, um, and, uh, and if they're doing an injections or injections, then, uh, probably the doctor would stop that for five days while then doing the fasting, the diet mm-hmm.

[00:25:21] Mareya: That's really amazing. I think that, you know, and something that I do recommend everybody do is a cleanse. So in a way you could really look at this as the same sort of thing, where we're giving the body a chance to. Rest the digestive system, the detoxifying organs, and you're literally doing some internal, you know, house cleaning.

[00:25:48] Um, and that's something that everybody can benefit from. But if you have a preexisting condition, uh, you know, this is also something to really take a look [00:26:00] at. And I think that's very exciting. Do you. I have another question. If you are an athlete, okay. You are training for a competition or you are, you know, right now I'm, I'm training for a competition.

[00:26:15] So I'm in a pretty strict eating regimen with my workouts. And I'm training pretty rigorously. I mean, can you do this in doing that also? Or is that just sort of too much on the body? 

[00:26:31] Dr. Joseph Antoun: We, um, we just published an journal of European physiology, an article, um, UN actually athlete men, not, not active athletes, that we went all the way there.

[00:26:42] And there's a secret here, which is fasting, right? Fasting is not where people could, people, a lot of people ask me why fasting is a big craze now, like why? And is it here to go away? Is it a fad or, or, and why is different than any low carry diet? The key word here [00:27:00] is stress fasting doesn't work because it's just a very low calorie diet.

[00:27:06] That's part of it, but it works because it's a stress. And when the stress induced rejuvenation of the cells and the stress induced rejuvenation of the muscle, and by the way, the stress hormone are high when you do ProLon. And because pro is not a starvation fast, it's nourished. We're seeing in our trials, in two of our trials, we saw that the lean bunny mess is fully protected.

[00:27:31] And then, so we went and we did this trial on the athletes to see what happens. And we, we were getting a lot of reports from NBA stars from, you know, God bless his souls. Kobe was, we used to do the Kobe trainer, used to put him on pro on, and we have many, many other players. I don't want to name them. Here, um, not to use their name for marketing, NHL player, NFL player, baseball players, and what they do, they do pro on.

[00:27:56] And they do peptides after protein, after pro on day six [00:28:00] onwards. And they report like a very, very lean cut on fat while preserving lean body mouth. 

[00:28:07] Mareya: Really, so you can preserve your muscle mass without compromising that and also shed body fat.

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[00:29:51] Dr. Joseph Antoun: We actually got, uh, this feedback from all these players and this sky team and the us Olympic team cycling. We went back, we did [00:30:00] the randomized specifically for this. And we, we are showing that you protect your body mass function when you do the fasting mimickin diet. So prolong will help you cut fat muscle.

[00:30:11] Doesn't get compromised. And think about it. So again, let's go back. What, what we love about what we do here, and this is why we do clinical trials and we're proud of them. Uh, going back to how we started this call is most nutrition company would not expose their food. We do it because we're going back and mimicking nature.

[00:30:28] So think about it hundred thousands of years ago. We are here. We're in nature. We're walking. There's no food. What the body has evolved to do? Oh, there's no food. I have some fat I'll break down fat to ketos. Why ketos? Because ketos are fat to, to nourish the brain. You wanna stay awake. Otherwise, if you faint, we will be exterminated as a race

[00:30:49] So the fats fat to feed the brain and the body protects with growth hormone. As a stress hormone protects the muscle. Because also, if you cannot walk, if the muscles get the system, [00:31:00] get compromised, then you're gonna faint. Then you start, you're gonna be slow. And now if you do 20 days of fast in metabolic rate will slow down and the, and the body has to go to muscle at there.

[00:31:10] So the five day of ProLon, we see that no, we're still in the acute phase and the muscle tone is high there's reservation. And remember we're feeding the body. So the body uses the food that we have to, to keep the muscle mass. And, um, and this is one of the secrets why athletes use Prolo today. 

[00:31:29] Mareya: So does it take a, a little while to see the results or like, is there sort of a delayed period where after you do the five days that you actually start to see results or do you start to see it as the five days are unfold right away?

[00:31:45] I'm curious if it's like a delayed reaction? No, 

[00:31:48] Dr. Joseph Antoun: it's a, it's a, it's a, it. Very fast action. So again, fasting is a stress and a crisis on the body. So you will on day one to prolong on. You'll be like, okay, I'm feeling [00:32:00] I'm detoxing. I feel lean. I feel like, but you'll be like, okay with it on day two, three, you're gonna feel like, okay, I'm in a crisis.

[00:32:08] I feel there are changes happening in my body, your cell, every cell of your body. This is the most experiential product. It will. Any nutrition company, any pill you, you swallow. It's just, like you said, takes time, et cetera. This is a fasting crisis on every cell. So you're gonna feel on day two and three, like especially the first cycle.

[00:32:27] If you're not what we call Metabo flexible. If you do keto in general and you you've have you, you had your body in the past, switch from car consumption to keto consumption. It'll be very easy for you. If that's the first time in your life, then two day two, until you're gonna feel something changing in your.

[00:32:44] And then day four and five you'll feel very euphoric because basically you're cruising. Now, your ketos are feeding the brain, which the brain loves the most. You sleep super well. You feel your very high of energy and, and you need just three, four hours of sleep and something is [00:33:00] high in you and where your cells are just autopiloting on self eating is when new ketones are high and it just, your body is, is going to that next level on performance on clarity.

[00:33:14] Metabolic health. So the results are they're very experiential every day and very fast. And a lot of the athletes, they would consume protein on day six and seven and eight to Reish their muscle and, and actually uses what you call the cleaning, the renewal, feed it fast, so that growth big and, and, and perform better.

[00:33:33] Interesting. 

[00:33:34] Mareya: Um, this is very fascinating to me. Um, I think that. You know, there is a lot of confusion about fasting and I think, um, you know, you can do it effectively and you can do it in a way that can put your body in a lot of danger. And I, I think it's really important that people understand. How to do it the right [00:34:00] way.

[00:34:00] And it seems like this kind of guided way would be really effective. Are there any anecdotal examples that you can just share on what you have personally seen? And you don't have to mention anybody, but. I'd just be curious, like maybe you have a, somebody that's tried it or a group and what kind of results that they have seen, because I think people always love to hear like, okay, how, what have other people experience with this?

[00:34:30] You know? 

[00:34:31] Dr. Joseph Antoun: Yeah. Well, we, we, as I mentioned, we, we, we crossed the 1 million for all users. So a lot of people have used to the run 14 countries, but. And by the way, it's, it's probably one of the biggest secrets in, in Hollywood. Um, you know, a lot of the big names there, people ask them how you stay healthy, look like this kid level.

[00:34:53] And, uh, because we have 14,000 clinics in the us that recommend prolong, but the highest concentration of doctors and [00:35:00] nutritionist that recommend prolong out in Los Angeles, San Francisco, Miami, and, and New York and, and, and Chicago and other cities. But. um, there are four types of benefits to answer your question.

[00:35:12] The benefit number one is weight. Um, you know, a lot of people wanna use that five to eight pounds in five days and, and fasting is the biggest weight signal you can send to the body to, you know, the body lives on cutting fat. Right? So, so in five days you're cutting a lot of fat detox is co-related to this.

[00:35:33] You, you mentioned that you're a hundred percent, right? There's a. Detox that happens with the fasting in canine and pre to the, and prolong to the body in, in its microbiome, changing to plant base. But it's also a cellular level of detox, right? There's so many companies there telling you a detox and a drink, a healthy drink, and, and that that's fine, but fasting.

[00:35:57] And when you cross the second and the third day, [00:36:00] uh, with our food is where you're also detaching your intracellular, uh, content, which is very important. Mm. The second level of benefits is more emotional. A lot of people, you know, between age 30 and, and, and, and 65 and 70, we're still getting more responsibilities in life.

[00:36:18] Our buddy is failing us down. We're more sedentary. We're picking up weight and we just get stuck and you wanna reset the buddy. You wanna wait and sell weight and cell, and you wanna feel this emotion of, Hey, I was able to achieve a diet. I mean, we're not even a diet. We're just five days. I was able to achieve something.

[00:36:37] Um, I feel my buddy has reset my buddy's restarting. It's a great kickstart. Um, I, I was able to do a five day of plan based diet. So, so it's, it's that reset that, that a lot of us need to kind of feel back on track and not being overwhelmed every day by, by, by what I call the learned helplessness against life and, and, and, [00:37:00] and demands of life.

[00:37:01] And number three is a nutritional. Relationship with food benefits. A lot of people say, wow, I've never knew that I, I needed a smaller portion and I would be super fine. And I actually feel high energy. Yeah. By eating less, they say I'm I'm. I got de addicted from late night. Snacking. A lot of us now, the worst thing you do to your life is just literally eating late at night before you sleep.

[00:37:24] And a lot of us would sit across the TV, the Netflix, the YouTube we're working late after family members are sleeping. And then we go and we snack. And now suddenly people say, I didn't know that I, um, I could go without that or without big portion. So that changing the relationship with food is the third benefit that we see.

[00:37:44] And the fourth benefit is is, is the performance, is this, you know, protecting anybody, mass, cutting fat, mental clarity, like you get out of it on day six, feeling like the best in your life, the brain, uh, uh, [00:38:00] mental experiential, emotional and physical. And you tell me how, how is that all possible? Because fasting impacts every cell of your body.

[00:38:08] Yeah. Your brain fasting. When you on ProLon your skin is fasting where we just did the randomized clinical trial on skin as well, showing, uh, many benefits on the skin because again, every cell of your body, plus the non body cell microbiome. Are all, um, rejuvenating when you do 

[00:38:25] Mareya: that. Yeah. I mean the microbiome to connection with skin, we just did a podcast about that as well.

[00:38:33] And it's just, it's so intrinsic to our skin health. I, I am really, really. You know, curious about the emotional benefits, um, that you've seen because, you know, coming out of COVID and just this global pandemic and the latent effects of that, you know, Not even just our day to [00:39:00] day lives and the stress of the economy and war and everything else going on, but just, we are all still processing that trauma.

[00:39:10] Um, and how fasting can impact that. I mean, do you feel, or do you see, you know, in the clinical studies that people who maybe were diagnosed as clinically depressed or have some sort of chemical imbalance that is affecting their, you know, their brain health, seeing that actually reverse. 

[00:39:38] Dr. Joseph Antoun: Um, I mean, you are using a question with drug claim reversed and depression, but, but you're talking again to the Pfizer of nutrition.

[00:39:46] So we have done in univers of Palomo has done a randomized clinical trial on using ProLon for depression. And it was, it was a feasibility trial, meaning just, you know, 10 patients with depression on ProLon and, and psychological [00:40:00] guidance and another arm, just psychological guidance. And you can read the results at the general of clinical psychology.

[00:40:06] So definitely better emotional self esteem, et cetera. And now we're gonna attack team with them on a new, bigger trial to show all the benefits, UN potentially the emotional benefits on people with depression, but, uh, the general of clinical psychology. If you Google that and you put the fasting mimicking diet.

[00:40:23] You will see the results on it. I, I don't want to go deep because these are drug claims and system does not allow an nutrition to talk about drug claim, but I 

[00:40:32] Mareya: understand, I, I know I kind of asked you a loaded question, but I'm asking more just generally your opinion too, like, is this. The answer that we're looking for.

[00:40:44] I mean, we, we have such, uh, a mental health issue nationwide. 

[00:40:50] Dr. Joseph Antoun: Yeah, yeah. I mean, globally. Right? So, so globally think about it this way. We used to live with much less stress. We used to be very active [00:41:00] and we used to eat little bit of food here and there, and then otherwise sleep early, um, you know, go into periods of, of healthy nutrition and or Nori.

[00:41:11] And in the last 40 years, we suddenly eat multiple times a day. And you remember these, the, the awful recommendation of eat six times a day. Um, and, and so we became obese. We, and stress increased, and then we eat more and the more we needed food, the more nutrition companies give us bad food, but taste good so that we eat more.

[00:41:30] Um, and it becames the race to the bottom where our body's, our body's not getting any rest from food, from stress, from lack of. And like you said, food is the only product we put in our body every day of our life. So let's start there. Let's give our buddy a break. Our, you know, we, we, we eat every day and, and multiple times a day, our body saying, well, I need a break.

[00:41:56] And, and I was tailored through hundreds of [00:42:00] thousands of years on plant earth to eat and not to. And only when I had a little bit of excess, I stored it in fact, and I would use it right away when there was no food. Now is all what you do is attack me with food. And by the way, I'm showing you the results of that.

[00:42:16] It's called diabetes. It's called cancer. It's called Alzheimer's, it's called cardiovascular disease. So we gotta go back, give our body a break, help it rejuvenate in the same. Let's go back to the formula one race car. If you keep racing on the track, you're gonna burn the engine in the tires. You gotta take a pitch.

[00:42:33] And the stop is when you rejuvenate. And this is where we as a, as a pro on or fasting, the diet have uncovered 20 years ago. And it took us 20 years because we do the right randomized trials on it to show people that your body also like your brain needs a break, and this is the way to do it. We made it easier with food.

[00:42:54] To help people still eat something, but that's something is very healthy and it's gonna help them fund their reation. [00:43:00] 

[00:43:00] Mareya: You know, I, uh, I'm 53 doctor and I went to get my body fat checked for this competition that I'm doing. And. I received a just general, you know, guide of what, you know, the average woman over 50 body fat acceptable measurements are.

[00:43:20] And it was 21 to 30%. And I was kind of shocked to see that because after the age of 50, also women over 50, have a. 30% higher chance of getting cardiovascular disease. Yeah. Immediately, just because of your age. So could the two be related and I mean, you know, it's not about to me, it's not about fat shaming.

[00:43:49] It's about. Really just looking and examining our habits and understanding that hormonally, we are changing lifestyle in some cases are changing [00:44:00] and therefore we have to just be more cognizant so that we don't get bombarded by these side effects that happen through menopause. 

[00:44:08] Dr. Joseph Antoun: And, and, and you just hit on a fraction of the point that I was trying to make at the beginning, which I hope our audience will learn.

[00:44:15] You know, the most out of this call, which is it's about aging. It's about bio and not chronological biological age. So you, you, you touch on menopause, which is an aging signal, an aging milestone. You touch on fat, you touch on cardiovascular. I will expand from that cancer as well. Doesn't happen most cancer at age.

[00:44:36] Alzheimer's now they started calling Alzheimer's diabetes type three. Mm. Right. And cardiovascular and diabetes. So what I'm trying to say is 90% of us will die among with, with one of these four diseases, and guess what they all happen at later stage in life. Mm-hmm therefore, guess what? Aging is the true.

[00:44:59] Trigger of [00:45:00] those. And therefore, guess what? Let's try to keep our biological age low or decelerate the, the aging process. So when Maria you're 53, but actually from the inside, you're 44, because that's the best way I can keep you away from the onset of one of the four killers that we're talking about.

[00:45:21] Right? Mm-hmm , if you were 43 now from the inside, you wouldn't be worried. About as much as you would be today or in 10 years about what's gonna happen to, to, to you whether it's cancer or Alzheimer's or diabetes or whatever. So the passion of our company, why we're saying longevity through nutrition is we try to, from a biological perspective, keep you younger with food.

[00:45:45] How can I send signals to your. To age slowly or to reverse aging. And one of our biggest discoveries that fasting does that when you told me, oh, it's like renewing your room, right? You throw the old stuff, you put the new stuff. What does that mean? That [00:46:00] means now that your room is not 10 years old is seven years old.

[00:46:03] I mean, it is 10 years old. You've had it for 10 years, but now that you change few things into it, it looks like it was three years ago. Right now, suddenly your, your room is seven years old, which by the way, It's more functional for another three years. Yeah. And that's exactly what we're trying to do.

[00:46:21] It's my biggest discovery coming out of medicine and joining this company. Is that we gotta work. The unit of measurement of the healthcare system should be the biological age of a person. Mm. And the BI and keeping a person young from the inside is the best way you can prevent all the big killers in American 

[00:46:40] Mareya: around the world.

[00:46:41] I think, let me just challenge you doctor. I think your next, uh, project should be. Uh, something to help determine what your true biological age is. I did that real age, uh, survey. I wanna actually know though, like I want something to read my [00:47:00] insides and my, my physicals tell me , 

[00:47:04] Dr. Joseph Antoun: there are many, uh, you're thinking the very right direction.

[00:47:06] And, and I had a Forbes article that I published, I think, three years ago, right. About that. There, there are many companies now that can help you guess what your biological age. Um, and we actually have a score ourself as well that we not, not our company, but it was developed by USC and Yale. Um, and, and you're right.

[00:47:25] We got a standardize there, there are like 20 come look at DNA, methylation, other looks at metabolic markers, et cetera. And we got a standardize and make that like cholesterol and triglyceride a reimbursed test because I can promise the healthcare system as now I'm talking with the policy. I can promise the, the, the, the health policy guidance of this country and, and the word health organization and, and every ministry of health around the world, that if they focus on keeping a person younger from the inside, the biological age, [00:48:00] measurement, you, this is the best way to gain healthy years of life and healthy use of lives.

[00:48:05] Meaning you're saving on the healthcare system. People stay healthy longer health system. Doesn't have to spend enough money on treating people every. And this is how you can, uh, everyone wins in that 

[00:48:17] Mareya: case. I love it. I, I could talk to you all day, but we're, we're, uh, closing in on our time together. I think this is really fascinating.

[00:48:26] What is the best place for people to find out more about El Nutra and your company? 

[00:48:35] Dr. Joseph Antoun: So our website L nutra.com and we build it more as a mission and passion website and does talk about our science. We have, um, we have a full menu tab on science. I recommend people read the articles there, medical articles and science articles.

[00:48:50] Um, and we do have, um, you know, a good section on the products. If you want to consume some, if you're inspired by the ProLon story, the five day fasting [00:49:00] mimic in diet, it can go to ProLon fast.com, P R O L O N. Fast for fasting pro on fast.com. And you can see all the information on the product and how you can access.

[00:49:11] Mareya: Wonderful. I always close every interview with one question. If you could have any meal created by anyone cooked by anyone, what would it be and who would make it? 

[00:49:28] Dr. Joseph Antoun: Oh, this I'm very, very biased in seeing this question we've created. A meal kit company as well. We didn't talk about it today called nutrition for longevity

[00:49:38] And first I did tell you it's reimbursed by, by now Medicaid and Medicaid. We're we're we're this we're the second company to be reimbursed by the first base on health, the health level. So I, I still wanna say we're the first food is medicine company and I actually eat from it every day. So I, I, I order my food nutrition for longevity.com gets [00:50:00] delivered to me every Tuesday.

[00:50:01] And I eat that food all the time, but it's a PEs. The, the food pattern that I order is a pescatarian food. Okay. Plant base, plus fish or seafood being the main source of the animal protein. And it's, 

[00:50:13] Mareya: what's your FA what's your favorite meal that you have? 

[00:50:17] Dr. Joseph Antoun: It's the salmon over the salad. Okay. The grill salmon over the salad, the fresh salad.

[00:50:23] Yeah, that 

[00:50:24] Mareya: sounds really good. Sounds really good. Right now I'm hungry. 

[00:50:27] Dr. Joseph Antoun: Some almond and uh, MEIA and the salad. 

[00:50:31] Mareya: Love it, Dr. Anton, thank you so much for sharing your wisdom about achieving longevity and how important fasting is in doing it the right way. And we'll be sure to put all of the links in the show notes for everybody to try out.

[00:50:48] And I think I wanna try it out. Myself, because I have my competition coming up and maybe, yeah, it would be the hack that I need to just get me across the, [00:51:00] uh, the finish line. 

[00:51:01] Dr. Joseph Antoun: I'm gonna send you, I'm gonna send you a video about the Olympic, uh, the us Olympic winner, um, uh, Skype. Christopherson talking about his pro on experience and, um, and there's the sky team in the, in the UK.

[00:51:15] I think they're, they're the gold medalist as well. They do prolong to cut, to cut fat while keeping the muscle. Function there. 

[00:51:23] Mareya: I love it. I I'm ready for it. 

[00:51:27] Dr. Joseph Antoun: yep. Fantastic. I'm gonna, I'm gonna follow up with you after this call. 

[00:51:33] Mareya: Hey, thank you so much for listening to this week's episode. I know you have a lot of choices out there.

[00:51:38] Of what to listen to what to watch. So it means a lot to me that you're here with me and Hey, if you love this content, would you hit the subscribe button? I want you around. I don't want you to just show up for one episode and leave. I want you here. Part of the conversation, a seat at this table, and while you're at it, would you share this with your friends and family?[00:52:00] 

[00:52:00] And if you take a screenshot and share it on your social media with a hashtag R F Y B L. Recipes for your best life. I'll make sure to personally give you a shout out and you may just be featured right here on the show. So until next time here's to living deliciously and being the chef of your best life.